Wyndham Midtown 45, located on 45th Street between 2nd and 3rd Avenues, is the perfect location for a visit to the "City that never sleeps." Step out your front door and find a city chock-full of famous landmarks. From the Empire State Building to the Statue of Liberty to Times Square to the United Nations. Your Midtown location, less than a quarter mile from Grand Central Station, makes traveling around Manhattan a breeze. . This building is half hotel and half refurbished timeshare condos.